Neepawa is located along the Yellowhead Highway 16 and Highway 5 / 45 minutes northeast of Brandon, the region’s largest centre, and 2 hours northwest of Winnipeg, the provincial capital. Neepawa is also located 1 hour from Riding Mountain National Park.

The Town features a 3,500 foot runway that is able to service air ambulance and small jets.

Neepawa has a taxi service provided by 1st Call Taxi 204-746-0034

The Canadian Pacific Railway services Neepawa for freight transportation.

Neepawa is serviced by Greyhound Bus lines.

Trucking services are provided by Gladstone Transfer and Gardewine, which maintain a depot.